SCHEMBL751982

SCHEMBL751982

Cc1cc(S(=O)(=O)O)ccc1N=Nc1c(O)ccc2cc(S(=O)(=O)O)ccc12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.70
CYP2C9 P11712 2/20 0.70
HIF1A Q16665 3/20 0.67
TSHR P16473 1/20 0.67
PTPRA P18433 1/20 0.67
PTPRB P23467 1/20 0.67
CYP2C19 P33261 1/20 0.67
RAPGEF4 Q8WZA2 1/20 0.67
HSD17B10 Q99714 1/20 0.67
ALDH1A1 P00352 3/20 0.66
SUMO2 P61956 1/20 0.59
SUMO1 P63165 1/20 0.59
SENP7 Q9BQF6 1/20 0.59
SENP3 Q9H4L4 1/20 0.59
SENP2 Q9HC62 1/20 0.59
SENP1 Q9P0U3 1/20 0.59
PTPN1 P18031 2/20 0.55
THRB P10828 3/20 0.54
ENPP2 Q13822 5/20 0.53
KMT2A Q03164 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8528180 1.00 CYP1A2 (0.70) CYP1A2CYP2C9HIF1ATSHRPTPRA
SCHEMBL30742587 1.00 CYP1A2 (0.70) CYP1A2CYP2C9HIF1ATSHRPTPRA
SCHEMBL28547156 0.99 CYP1A2 (0.68) CYP1A2CYP2C9HIF1ATSHRPTPRA
SCHEMBL15424240 0.94 HIF1A (0.76) CYP1A2CYP2C9HIF1ATSHRPTPRA
SCHEMBL15424214 0.91 CYP1A2 (0.68) CYP1A2CYP2C9HIF1ATSHRPTPRA
SCHEMBL5160460 0.90 CYP1A2 (0.71) CYP1A2CYP2C9HIF1ATSHRPTPRA
SCHEMBL12955458 0.90 CYP1A2 (0.71) CYP1A2CYP2C9HIF1ATSHRPTPRA
SCHEMBL1435843 0.89 CYP1A2 (0.69) CYP1A2CYP2C9HIF1ATSHRPTPRA
SCHEMBL1435839 0.89 CYP1A2 (0.69) CYP1A2CYP2C9HIF1ATSHRPTPRA
SCHEMBL19695889 0.83 CYP1A2 (0.60) CYP1A2CYP2C9HIF1ATSHRPTPRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050147673-A1 Directly compressible sustained release formulation containing microcrystalline cellulose J. RETTENMAIER & SOEHNE GMBH + CO. KG (DE) 2005-07-07 US claimed
US-6106865-A MIXTURE OF MICROCRYSTALLINE CELLULOSE, COMPRESSIBILITY, SILICA AND SURFACTANTS EDWARD MENDELL CO., INC. (US) 2000-08-22 US claimed
US-5858412-A FORMING AQUEOUS SLURRY OF MICROCRYSTALLINE CELLULOSE AND COMPRESSIBILITY AUGMENTING AGENT, DRYING TO FORM AGGLOMERATED PARTICLES, ADDING ACTIVE AGENT, INCORPORATING SUSTAINED-RELEASE CARRIER EDWARD MENDELL CO., INC. (US) 1999-01-12 US claimed
US-5430074-A Methacrylic resins JENERIC/PENTRON, INCORPORATED (US) 1995-07-04 US claimed
US-20250255843-A1 COMPOSITIONS COMPRISING CYSTEINE PRODRUGS AND METHODS USING THEREOF Nature's Fusions, LLC 2025-08-14 US disclosed
US-20240207209-A1 Threonate Compounds and Methods of Use Thereof NEUROCENTRIA, INC. 2024-06-27 US disclosed
WO-2024026124-A1 COMPOSITIONS COMPRISING CYSTEINE PRODRUGS AND METHODS USING THEREOF PETERSON MATTHEW (US) 2024-02-01 WO disclosed
US-20230355556-A1 Threonate Compounds and Methods of Use Thereof NEUROCENTRIA, INC. 2023-11-09 US disclosed
US-20230116091-A1 Threonate Compounds and Methods of Use Thereof NEUROCENTRIA, INC. 2023-04-13 US disclosed
US-20220249412-A1 Threonate Compounds and Methods of Use Thereof NEUROCENTRIA, INC. 2022-08-11 US disclosed
US-11298330-B2 Magnesium compositions and methods of use NEUROCENTRIA, INC. (US) 2022-04-12 US disclosed
US-20210393561-A1 Threonate Compounds and Methods of Use Thereof NEUROCENTRIA, INC. 2021-12-23 US disclosed
US-20030099702-A1 Pharmaceutical excipient having improved compressibility PENWEST PHARMACEUTICALS CO. 2003-05-29 US disclosed
EP-1289381-A2 LOW-STAINING ORANGE FOOD COLORING COMPOSITION PepsiCo, Inc. (US) 2003-03-12 EP disclosed
US-20020182259-A1 Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose J. RETTENMAIER & SOEHNE GMBH + CO. KG (DE) 2002-12-05 US disclosed
US-20020122851-A1 Low-staining orange food coloring composition PEPSICO, INC. 2002-09-05 US disclosed
US-6395303-B1 Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose EDWARD MENDELL CO., INC. 2002-05-28 US disclosed
WO-2001091585-A2 LOW-STAINING ORANGE FOOD COLORING COMPOSITION PEPSICO, INC. (US) 2001-12-06 WO disclosed
US-6106865-A MIXTURE OF MICROCRYSTALLINE CELLULOSE, COMPRESSIBILITY, SILICA AND SURFACTANTS EDWARD MENDELL CO., INC. (US) 2000-08-22 US disclosed
US-5430074-A Methacrylic resins JENERIC/PENTRON, INCORPORATED (US) 1995-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210393561-A1 Threonate Compounds and Methods of Use Thereof SLC18A2, SLC1A2, SLC18A3 CYP1A2 4821/4885CYP2C9 4796/4885HIF1A 3938/4885
US-20240207209-A1 Threonate Compounds and Methods of Use Thereof SLC18A2, SLC1A2, SLC18A3 CYP1A2 4821/4885CYP2C9 4796/4885HIF1A 3938/4885
US-20230116091-A1 Threonate Compounds and Methods of Use Thereof SLC18A2, SLC1A2, SLC18A3 CYP1A2 4821/4885CYP2C9 4796/4885HIF1A 3938/4885
US-20250255843-A1 COMPOSITIONS COMPRISING CYSTEINE PRODRUGS AND METHODS USING THEREOF AHCY, MGMT, CBS CYP1A2 1349/4885CYP2C9 307/4885HIF1A 4468/4885
US-20220249412-A1 Threonate Compounds and Methods of Use Thereof SLC18A2, SLC1A2, SLC18A3 CYP1A2 4821/4885CYP2C9 4796/4885HIF1A 3938/4885
US-11298330-B2 Magnesium compositions and methods of use SLC5A6, SLC6A6, SLC6A5 CYP1A2 520/4885CYP2C9 367/4885HIF1A 4640/4885
US-20230355556-A1 Threonate Compounds and Methods of Use Thereof SLC18A2, SLC1A2, SLC18A3 CYP1A2 4821/4885CYP2C9 4796/4885HIF1A 3938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.