Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | PTPRA | P18433 | 1/20 | 0.69 |
| ▸ | PTPRB | P23467 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MPL | P40238 | 4/20 | 0.57 |
| ▸ | CTRC | Q99895 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435843 | 1.00 | CYP1A2 (0.69) | CYP1A2HIF1ACYP2C9TSHRPTPRA | |
| SCHEMBL12955458 | 0.99 | CYP1A2 (0.71) | CYP1A2HIF1ACYP2C9TSHRPTPRA | |
| SCHEMBL5160460 | 0.99 | CYP1A2 (0.71) | CYP1A2HIF1ACYP2C9TSHRPTPRA | |
| SCHEMBL28547156 | 0.90 | CYP1A2 (0.68) | CYP1A2HIF1ACYP2C9TSHRPTPRA | |
| SCHEMBL751982 | 0.89 | CYP1A2 (0.70) | CYP1A2HIF1ACYP2C9TSHRPTPRA | |
| SCHEMBL8528180 | 0.89 | CYP1A2 (0.70) | CYP1A2HIF1ACYP2C9TSHRPTPRA | |
| SCHEMBL30742587 | 0.89 | CYP1A2 (0.70) | CYP1A2HIF1ACYP2C9TSHRPTPRA | |
| SCHEMBL1435840 | 0.88 | THRB (0.67) | CYP1A2HIF1ACYP2C9TSHRPTPRA | |
| SCHEMBL29625856 | 0.88 | THRB (0.67) | CYP1A2HIF1ACYP2C9TSHRPTPRA | |
| SCHEMBL1743198 | 0.88 | THRB (0.67) | CYP1A2HIF1ACYP2C9TSHRPTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070231283-A1 | Process for bleaching keratin fibers | PROCTER & GAMBLE COMPANY, THE | 2007-10-04 | — | — | US | claimed |
| EP-1759684-A1 | Process for bleaching keratin fibers | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | claimed |
| EP-1844109-B1 | USE OF CATIONIC AZACYANINE DYES FOR COLORING KERATIN FIBERS | PROCTER & GAMBLE (US) | 2011-03-30 | — | — | EP | disclosed |
| US-20100278767-A1 | Lightening Agents and/or Dyes that Contain Aldehyde(s) | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | US | disclosed |
| EP-1825883-B1 | Agents for coloring keratin fibers | PROCTER & GAMBLE (US) | 2010-04-14 | — | — | EP | disclosed |
| US-7658771-B2 | Coloring agents for keratin fibers | THE PROCTER & GABLE COMPANY (US) | 2010-02-09 | — | — | US | disclosed |
| US-7658770-B2 | Agents for coloring keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2010-02-09 | — | — | US | disclosed |
| EP-1847250-B1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | PROCTER & GAMBLE (US) | 2009-12-23 | — | — | EP | disclosed |
| US-20090165221-A1 | Agents for Coloring Keratin Fibers | WELLA OPERATIONS US, LLC | 2009-07-02 | — | — | US | disclosed |
| US-7553337-B2 | Hair colorants for simultaneous dyeing and brightening of keratin fibers | WELLA AG (DE) | 2009-06-30 | — | — | US | disclosed |
| US-20090158532-A1 | For the simultaneous lightening and coloring of keratin fibers; oxidizing agent and azo dye such as 2-[{4-[(4,5-dimethyl-1,3-thiazol-2-yl) diazenyl ]phenyl}(ethyl)amino]-N,N,N-trimethylethanaminium bromide | WELLA OPERATIONS US, LLC | 2009-06-25 | — | — | US | disclosed |
| US-20070022545-A1 | Use of cationic azacyanine dyes for coloring keratin fibers | PROCTER & GAMBLE COMPANY, THE | 2007-02-01 | — | — | US | disclosed |
| US-20070011821-A1 | Agents for coloring keratin fibers | WELLA OPERATIONS US, LLC | 2007-01-18 | — | — | US | disclosed |
| US-20070000071-A1 | Colorants comprising cationic azacyanine dyes | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | disclosed |
| US-20060242772-A1 | Reductive colouring system for keratin fibres | THE PROCTER & GAMBLE COMPANY | 2006-11-02 | — | — | US | disclosed |
| US-20060230548-A1 | Reductive colorant for keratin fibres | THE PROCTER & GAMBLE COMPANY | 2006-10-19 | — | — | US | disclosed |
| WO-2006107595-A1 | REDUCTIVE COLORANT FOR KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006107594-A1 | REDUCTIVE COLOURING SYSTEM FOR KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |
| EP-1707187-A1 | Reductive colorant for keratin fibres | Wella Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | disclosed |
| EP-1707188-A1 | Reductive colouring system for keratin fibres | Wella Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090165221-A1 | Agents for Coloring Keratin Fibers | KRT18, IK, KRTCAP2 | CYP1A2 3605/4885HIF1A 3118/4885CYP2C9 3602/4885 |
| US-20090158532-A1 | For the simultaneous lightening and coloring of keratin fibers; oxidizing agent and azo dye such as 2-[{4-[(4,5-dimethyl-1,3-thiazol-2-yl) diazenyl ]phenyl}(ethyl)amino]-N,N,N-trimethylethanaminium bromide | KRT18, TPM4, TUBB1 | CYP1A2 1062/4885HIF1A 1674/4885CYP2C9 2073/4885 |
| US-20070022545-A1 | Use of cationic azacyanine dyes for coloring keratin fibers | KRT18, AZI2, MKI67 | CYP1A2 1505/4885HIF1A 3662/4885CYP2C9 1504/4885 |
| US-20070011821-A1 | Agents for coloring keratin fibers | KRT18, IK, DSG1 | CYP1A2 3840/4885HIF1A 3845/4885CYP2C9 4116/4885 |
| US-20060242772-A1 | Reductive colouring system for keratin fibres | KRT18, OAT, COX6C | CYP1A2 665/4885HIF1A 2117/4885CYP2C9 514/4885 |
| US-20070000071-A1 | Colorants comprising cationic azacyanine dyes | KRT18, IK, NUP205 | CYP1A2 2322/4885HIF1A 4464/4885CYP2C9 2484/4885 |
| US-20100278767-A1 | Lightening Agents and/or Dyes that Contain Aldehyde(s) | CCR3, CBR3, CCRL2 | CYP1A2 1833/4885HIF1A 3018/4885CYP2C9 1410/4885 |
| US-20060230548-A1 | Reductive colorant for keratin fibres | KRT18, COX6C, CYC1 | CYP1A2 438/4885HIF1A 1416/4885CYP2C9 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.