Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517561 | 0.86 | LCK (0.42) | NFE2L2ALOX5RELACA1MAPT | |
| SCHEMBL7517571 | 0.86 | LCK (0.42) | NFE2L2ALOX5RELACA1MAPT | |
| SCHEMBL4038715 | 0.80 | RELA (0.54) | NFE2L2RELATUBB1KDM4ECYP1A2 | |
| SCHEMBL27230111 | 0.78 | ALDH1A1 (0.48) | NFE2L2RELACA1MAPTSMN1; SMN2 | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1793692 | 0.78 | NFE2L2 (0.74) | NFE2L2PTGS1PTGS2ALOX5RELA | |
| SCHEMBL318785 | 0.78 | NFE2L2 (0.74) | NFE2L2PTGS1PTGS2ALOX5RELA | |
| SCHEMBL318786 | 0.78 | NFE2L2 (0.74) | NFE2L2PTGS1PTGS2ALOX5RELA | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305582 | 0.78 | NFE2L2 (0.74) | NFE2L2PTGS1PTGS2ALOX5RELA | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305580 | 0.78 | NFE2L2 (0.74) | NFE2L2PTGS1PTGS2ALOX5RELA | |
| SCHEMBL10719726 | 0.78 | CYP1A2 (0.47) | NFE2L2PTGS1PTGS2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506314-B1 | Process for preparing vinylically-unsaturated compounds | DOW CHEMICAL CO (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5247037-A | Heat resistance, lower water absorption | THE DOW CHEMICAL COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| US-5243068-A | Alkenylation with organic halides | THE DOW CHEMICAL COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0506314-A2 | Process for preparing vinylically-unsaturated compounds | THE DOW CHEMICAL COMPANY (US) | 1992-09-30 | — | — | EP | disclosed |
| US-5136069-A | Reacting with halogenated organic compound in presence of palladium complex catalyst and inorganic hydrogen halide acceptor | THE DOW CHEMICAL COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| US-4783514-A | Polymeric monoarylcyclobutane compositions | THE DOW CHEMICAL COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| EP-0242033-A2 | Compositions comprising arylcyclobutene and polymeric compositions prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1987-10-21 | — | — | EP | disclosed |
| WO-1987005303-A1 | COMPOSITIONS COMPRISING ARYLCYCLOBUTENE AND POLYMERIC COMPOSITIONS PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1987-09-11 | — | — | WO | disclosed |