Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520344 | 0.81 | RET (0.45) | RETKDRCYP3A4ALOX15ALDH1A1 | |
| SCHEMBL7527043 | 0.77 | CHRNA1 (0.45) | RETKDRCYP3A4ALOX15ALDH1A1 | |
| SCHEMBL3306471 | 0.76 | CYP19A1 (0.43) | CRHBPCRHR2CYP3A4ALOX15MAPT | |
| SCHEMBL2337166 | 0.76 | CYP19A1 (0.43) | CRHBPCRHR2CYP3A4ALOX15MAPT | |
| SCHEMBL7521676 | 0.76 | MAPT (0.43) | CYP3A4ALOX15ALDH1A1MAPTHPGD | |
| SCHEMBL8484519 | 0.74 | CYP19A1 (0.47) | CYP3A4ALOX15ALDH1A1MAPTHPGD | |
| SCHEMBL7516218 | 0.73 | MEN1 (0.40) | CYP3A4ALOX15ALDH1A1MAPTHSP90AA1 | |
| SCHEMBL7530287 | 0.72 | OPRD1 (0.37) | CYP3A4ALOX15PDK2PGRALDH1A1 | |
| SCHEMBL7520906 | 0.72 | KDM4E (0.39) | CYP3A4ALOX15MAPTMAOBMAOA | |
| SCHEMBL7762100 | 0.71 | IDO1 (0.38) | CYP3A4ALOX15ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743311-B1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | KAO CORP (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5876703-A | CELL DIFFERENTIATION OF HAIR MATRIX CELLS | KAO CORPORATION (JP) | 1999-03-02 | — | — | US | disclosed |
| US-5702691-A | Flavanonol derivatives and hair-nourishing, hair growing compositions containing the derivatives | KAO CORPORATION (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0743311-A1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | Kao Corporation (JP) | 1996-11-20 | — | — | EP | disclosed |