SCHEMBL752082

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754178	0.87	ALDH1A1 (0.37)	LIPGPOLBRECQLALDH1A1CYP1A2
	SCHEMBL754220	0.84	POLB (0.39)	LIPGPOLBRECQLALDH1A1CYP1A2
	SCHEMBL756359	0.83	LIPG (0.43)	LIPGPOLBRECQLTSHRMAOB
	SCHEMBL754370	0.82	LIPG (0.47)	LIPGPOLBRECQLMAOBNR4A2
	SCHEMBL753011	0.79	JAK2 (0.45)	LIPGPOLBRECQLTSHRMAOB
	SCHEMBL754314	0.76	LIPG (0.48)	LIPGPOLBRECQLMAOBNR4A2
	SCHEMBL754144	0.75	LIPG (0.42)	LIPGPOLBRECQLALDH1A1MEN1
	SCHEMBL754596	0.75	LIPG (0.42)	LIPGALDH1A1MEN1KMT2ACYP3A4
	SCHEMBL755667	0.72	ALKBH1 (0.43)	LIPGMAOBMAOA
	SCHEMBL753054	0.71	LIPG (0.39)	LIPGALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.