Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 12/20 | 0.58 |
| ▸ | MMP13 | P45452 | 10/20 | 0.58 |
| ▸ | MMP1 | P03956 | 7/20 | 0.58 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 5/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522070 | 1.00 | MMP9 (0.58) | MMP9MMP13MMP1ADAM17HSD17B10 | |
| SCHEMBL7381562 | 0.87 | SLC1A3 (0.55) | MMP9MMP13MMP1HSD17B10MMP2 | |
| SCHEMBL7413838 | 0.82 | MMP9 (0.53) | MMP9MMP13MMP1ADAM17HSD17B10 | |
| SCHEMBL7414576 | 0.81 | MMP9 (0.51) | MMP9MMP13MMP1ADAM17HSD17B10 | |
| SCHEMBL7416701 | 0.79 | ALDH1A1 (0.58) | MMP9MMP13MMP1ADAM17HSD17B10 | |
| SCHEMBL7417565 | 0.77 | MMP9 (0.64) | MMP9MMP13MMP1ADAM17HSD17B10 | |
| SCHEMBL1565606 | 0.76 | MMP13 (0.58) | MMP9MMP13MMP1MMP2MMP8 | |
| SCHEMBL5226437 | 0.76 | MMP13 (0.58) | MMP9MMP13MMP1MMP2MMP8 | |
| SCHEMBL7419763 | 0.75 | MMP13 (0.56) | MMP9MMP13MMP1ADAM17HSD17B10 | |
| SCHEMBL7461414 | 0.75 | MMP13 (0.56) | MMP9MMP13MMP1ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934267-B1 | ALPHA-AMINO SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE INHIBITORS | UPJOHN CO (US) | 2002-01-30 | — | — | EP | claimed |