Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064643 | 0.82 | MEN1 (0.50) | FAAHEPHX2MEN1KMT2A | |
| SCHEMBL7523266 | 0.79 | FAAH (0.41) | FAAHEPHX2OPRM1OPRK1OPRD1 | |
| SCHEMBL7523786 | 0.77 | ELANE (0.38) | FAAHEPHX2MEN1KMT2A | |
| SCHEMBL5475255 | 0.74 | HSD11B1 (0.44) | FAAHEPHX2MEN1KMT2A | |
| SCHEMBL7523248 | 0.74 | EPHX2 (0.43) | FAAHEPHX2MEN1KMT2A | |
| SCHEMBL419753 | 0.73 | MEN1 (0.59) | FAAHEPHX2OPRM1OPRK1OPRD1 | |
| SCHEMBL15220087 | 0.69 | ALOX5AP (0.46) | FAAHEPHX2OPRM1OPRK1OPRD1 | |
| SCHEMBL8077581 | 0.69 | OPRM1 (0.45) | OPRM1OPRK1OPRD1 | |
| SCHEMBL29151362 | 0.66 | KDM1A (0.46) | EPHX2OPRK1 | |
| SCHEMBL30688050 | 0.66 | KDM1A (0.46) | EPHX2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869938-B1 | NOVEL VINYL SULFIDE COMPOUNDS AND A PROCESS FOR THEIR PREPARATION | LUMIGEN INC (US) | 2002-10-16 | — | — | EP | disclosed |
| EP-0842168-B1 | PROCESS FOR THE PREPARATION OF 1,2-DIOXETANE COMPOUNDS AND NOVEL SULFUR-SUBSTITUTED 1,2-DIOXETANE COMPOUNDS AS INTERMEDIATES | LUMIGEN INC (US) | 2002-02-20 | — | — | EP | disclosed |