Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269355 | 0.77 | MAPT (0.37) | EPHX2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL30978073 | 0.77 | MAPT (0.37) | EPHX2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7523253 | 0.74 | FAAH (0.45) | EPHX2FAAHMEN1KMT2A | |
| Acrylic Acid SCHEMBL11105271 | 0.73 | ALDH1A1 (0.36) | EPHX2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL5475255 | 0.73 | HSD11B1 (0.44) | EPHX2ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL29809124 | 0.71 | MEN1 (0.48) | EPHX2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL345587 | 0.71 | MEN1 (0.48) | EPHX2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8064643 | 0.68 | MEN1 (0.50) | EPHX2ALDH1A1MAPTFAAHCNR2 | |
| SCHEMBL237723 | 0.65 | GRIN2D (0.43) | EPHX2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8632526 | 0.65 | ALOX5AP (0.37) | ALDH1A1KDM4EMAPTHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869938-B1 | NOVEL VINYL SULFIDE COMPOUNDS AND A PROCESS FOR THEIR PREPARATION | LUMIGEN INC (US) | 2002-10-16 | — | — | EP | disclosed |
| EP-0842168-B1 | PROCESS FOR THE PREPARATION OF 1,2-DIOXETANE COMPOUNDS AND NOVEL SULFUR-SUBSTITUTED 1,2-DIOXETANE COMPOUNDS AS INTERMEDIATES | LUMIGEN INC (US) | 2002-02-20 | — | — | EP | disclosed |