Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3483188 | 0.83 | DRD2 (0.61) | ALDH1A1DRD2DRD3MAPTHTR1A | |
| SCHEMBL3951003 | 0.79 | SLC6A2 (0.43) | DRD2DRD3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL255189 | 0.78 | HTR1A (0.68) | ALDH1A1HSD17B10DRD2DRD3DRD4 | |
| SCHEMBL7524534 | 0.78 | HTR1A (0.68) | ALDH1A1HSD17B10DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL16528267 | 0.77 | MAPT (0.69) | ALDH1A1HSD17B10DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL787250 | 0.77 | MAPT (0.69) | ALDH1A1HSD17B10DRD2DRD3DRD4 | |
| Bromide SCHEMBL10621563 | 0.77 | HTR1A (0.66) | ALDH1A1HSD17B10DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL15938311 | 0.76 | HTR1A (0.64) | ALDH1A1HSD17B10DRD2DRD3DRD4 | |
| SCHEMBL5805251 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HSD17B10DRD2DRD3DRD4 | |
| SCHEMBL2209185 | 0.74 | ADRB1 (0.58) | ALDH1A1DRD2DRD3HTR1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128231-A1 | Aryl-indane compounds | EASTMAN CHEMICAL COMPANY | 2002-09-12 | — | — | US | disclosed |
| WO-2002030915-A2 | ARYL-INDANE COMPOUNDS FOR USE AS INHIBITORS OF P-GLYCOPROTEIN MEDIATED TRANSPORT | AVLAN LIMITED (GB) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128231-A1 | Aryl-indane compounds | ABCB1, ABCC1, ABCG2 | ALDH1A1 454/4885HSD17B10 2203/4885DRD2 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.