SCHEMBL255189

SCHEMBL255189

CCOc1ccccc1N1CCNCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 6/20 0.68
SLC6A2 P23975 4/20 0.68
SLC6A4 P31645 4/20 0.68
SLC6A3 Q01959 3/20 0.68
HTR3A P46098 3/20 0.68
DRD2 P14416 2/20 0.68
DRD3 P35462 2/20 0.68
HTR6 P50406 2/20 0.68
HTR3E A5X5Y0 1/20 0.68
HTR3B O95264 1/20 0.68
ADRB1 P08588 1/20 0.68
CYP2C19 P33261 1/20 0.68
HTR3D Q70Z44 1/20 0.68
HTR3C Q8WXA8 1/20 0.68
SIGMAR1 Q99720 1/20 0.68
MAPT P10636 2/20 0.66
LMNA P02545 1/20 0.66
ALDH1A1 P00352 3/20 0.61
HSD17B10 Q99714 1/20 0.61
DRD4 P21917 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7524534 1.00 HTR1A (0.68) HTR1ASLC6A2SLC6A4SLC6A3HTR3A
Hydrochloric Acid SCHEMBL787250 0.98 MAPT (0.69) HTR1ASLC6A2SLC6A4SLC6A3HTR3A
Bromide SCHEMBL10621563 0.98 HTR1A (0.66) HTR1ASLC6A2SLC6A4SLC6A3HTR3A
Hydrochloric Acid SCHEMBL16528267 0.98 MAPT (0.69) HTR1ASLC6A2SLC6A4SLC6A3HTR3A
Hydrochloric Acid SCHEMBL15938311 0.97 HTR1A (0.64) HTR1ASLC6A2SLC6A4SLC6A3HTR3A
SCHEMBL14984391 0.94 HTR1A (0.61) HTR1ASLC6A2SLC6A4SLC6A3HTR3A
Hydrochloric Acid SCHEMBL252532 0.93 LMNA (0.61) HTR1ASLC6A2SLC6A4SLC6A3HTR3A
SCHEMBL3805551 0.93 HTR1A (0.61) HTR1ASLC6A2SLC6A4SLC6A3HTR3A
SCHEMBL5805251 0.90 ALDH1A1 (0.58) HTR1ASLC6A2SLC6A4SLC6A3HTR3A
SCHEMBL6927912 0.87 HTR1A (0.64) HTR1ASLC6A2SLC6A4SLC6A3HTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 595 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112831206-B Inorganic oxide dispersion with controllable water content and preparation method thereof 凯斯科技股份有限公司 2022-12-30 CN claimed
CN-106260500-A The method promoting papain activity 山东理工大学 2017-01-04 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
US-20260092134-A1 Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery UNIV JOHNS HOPKINS (US) 2026-04-02 US disclosed
US-12527746-B2 Peptide/particle delivery systems THE JOHNS HOPKINS UNIVERSITY (US) 2026-01-20 US disclosed
EP-4642434-A2 LIPID COMPOSITIONS ON THE BASIS OF IONIZABLE LIPIDS, USE FOR DELIVERY TO IMMUNE CELLS Life Technologies Corporation (US) 2025-11-05 EP disclosed
US-12458700-B2 Amine-containing transfection reagents and methods for making and using same Life Technologies Corporation (US) 2025-11-04 US disclosed
US-12371522-B2 Bioreducible poly (beta-amino ester)s for siRNA delivery THE JOHNS HOPKINS UNIVERSITY (US) 2025-07-29 US disclosed
EP-4381284-B1 LIGAND-TARGET INTERACTION ANALYSIS BY PHOTOCHEMICALLY INDUCED DYNAMIC NUCLEAR POLARIZATION (PHOTO-CIDNP) ENHANCED NMR SPECTROSCOPY ETH ZUERICH (CH) 2025-07-09 EP disclosed
US-20250136737-A1 MULTICOMPONENT DEGRADABLE CATIONIC POLYMERS THE JOHNS HOPKINS UNIVERSITY 2025-05-01 US disclosed
US-4563458-A CIRCULATORY SYSTEM DISORDERS BAYER AKTIENGESELLSCHAFT (DE) 1986-01-07 US disclosed
US-4547505-A ANTIULCER, ANTIPHLOGISTIC, AND ANTISECRETORY AGENT DEGUSSA AKTIENGESELLSCHAFT (DE) 1985-10-15 US disclosed
EP-0114374-A1 Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines BAYER AG (DE) 1984-08-01 EP disclosed
US-4460593-A Carbostyril derivatives, and central nervous system controlling agents containing the carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-07-17 US disclosed
US-4455422-A ANTIHISTAMINES, CNS CONTROLLERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-06-19 US disclosed
US-4370330-A Method of enhancing circulation with piperazines MERZ & COMPANY (DE) 1983-01-25 US disclosed
US-4320128-A HYPOTENSIVE AGENTS BEECHAM GROUP LIMITED (GB) 1982-03-16 US disclosed
EP-0017352-A2 Chromanone derivatives, a process for their preparation, compositions containing them BEECHAM GROUP PLC (GB) 1980-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527746-B2 Peptide/particle delivery systems VEGFA, IGF2BP2, MSTN HTR1A 1346/4885SLC6A2 3113/4885SLC6A4 3256/4885
US-20250136737-A1 MULTICOMPONENT DEGRADABLE CATIONIC POLYMERS PEF1, FIBP, PARN HTR1A 2004/4885SLC6A2 3748/4885SLC6A4 3522/4885
US-12458700-B2 Amine-containing transfection reagents and methods for making and using same SNRPA, NUDT21, SOAT2 HTR1A 2495/4885SLC6A2 429/4885SLC6A4 767/4885
US-12371522-B2 Bioreducible poly (beta-amino ester)s for siRNA delivery AARS1, SLC43A1, PHAX HTR1A 4516/4885SLC6A2 1007/4885SLC6A4 1368/4885
US-20260092134-A1 Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery SLC43A1, SLC7A5, SLC7A1 HTR1A 4712/4885SLC6A2 749/4885SLC6A4 1172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.