Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2578522 | 0.83 | GNAI3 (0.43) | GNAI3GNAO1GNAI1SIGMAR1 | |
| SCHEMBL1128451 | 0.80 | SIGMAR1 (0.37) | GNAI3GNAO1GNAI1SIGMAR1 | |
| SCHEMBL9990034 | 0.75 | SIGMAR1 (0.36) | GNAI3GNAO1GNAI1SIGMAR1 | |
| SCHEMBL8537023 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL20141887 | 0.71 | L3MBTL1 (0.35) | GNAI3GNAO1GNAI1 | |
| SCHEMBL15979334 | 0.71 | — | — | |
| SCHEMBL22045062 | 0.70 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL4358748 | 0.69 | — | — | |
| SCHEMBL4745377 | 0.69 | CA2 (0.38) | SIGMAR1 | |
| SCHEMBL28605719 | 0.69 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040111-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999031099-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |