Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272135 | 0.85 | HTR2B (0.36) | HTR2AHTR2CHRH1MAOAMAOB | |
| SCHEMBL8798181 | 0.85 | TBXA2R (0.36) | HTR2AHTR2CHRH1 | |
| SCHEMBL11278667 | 0.83 | MAOB (0.42) | HTR2AHTR2CHRH1MAOAMAOB | |
| SCHEMBL7522168 | 0.83 | MAPT (0.38) | HTR2AHTR2CHRH1TERTKMT2A | |
| SCHEMBL7526493 | 0.83 | DRD2 (0.39) | MAOB | |
| SCHEMBL7520603 | 0.83 | DRD2 (0.39) | HTR2AHTR2CHRH1 | |
| SCHEMBL8797797 | 0.81 | IMPDH2 (0.36) | HTR2AHTR2CHRH1TERTKMT2A | |
| SCHEMBL7525559 | 0.81 | CYP3A4 (0.36) | MAOAMAOBKMT2ANPC1LMNA | |
| SCHEMBL8797546 | 0.80 | HTR7 (0.36) | HTR2AHTR2CHRH1KMT2ANPC1 | |
| SCHEMBL11271280 | 0.80 | MAPT (0.47) | HTR2AHTR2CKMT2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151553-A1 | Chemokine receptor antagonists and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-17 | — | — | US | disclosed |
| US-6433165-B1 | ANTIINFLAMMATORY AGENTS | MILLENNIUM PHARMACEUTICALS, INC. | 2002-08-13 | — | — | US | disclosed |
| US-6323206-B1 | ANTIINFLAMMATORY AGENTS AND VIRICIDES FOR AIDS WITH CYTOKINESAND CHEMOKINES | MILLENNIUM PHARMACEUTICALS, INC. | 2001-11-27 | — | — | US | disclosed |
| US-4335122-A | DIURETICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151553-A1 | Chemokine receptor antagonists and methods of use therefor | CCR1, CCR2, CCR5 | HTR2A 2004/4885HTR2C 1550/4885HRH1 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.