Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600065 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2CA1CA2CA14KMT2A | |
| SCHEMBL14827564 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2CA1CA2CA14KMT2A | |
| SCHEMBL635059 | 0.78 | KMT2A (0.40) | CA1CA2CA14KMT2ACA12 | |
| SCHEMBL635058 | 0.78 | KMT2A (0.40) | CA1CA2CA14KMT2ACA12 | |
| SCHEMBL7528046 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2CA1CA2CA14KMT2A | |
| SCHEMBL897666 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL7212483 | 0.78 | CA1 (0.38) | SMN1; SMN2CA1CA2KMT2AMEN1 | |
| SCHEMBL3212385 | 0.76 | ALDH1A1 (0.40) | CA2KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL526639 | 0.76 | DGAT1 (0.41) | SMN1; SMN2CA1CA2CA14KMT2A | |
| SCHEMBL27926275 | 0.76 | KDM4E (0.33) | SMN1; SMN2CA1CA2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108933-B | Synthesis method of lacosamide | 上药康丽（常州）药业有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-113461679-B | Synthesis of benzazepine isatin compound | 石药集团中奇制药技术（石家庄）有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-113461679-A | Synthesis of benzazepine isatin compound | 石药集团中奇制药技术（石家庄）有限公司 | 2021-10-01 | — | — | CN | claimed |
| EP-3328914-A1 | BLOCKED POLYISOCYANATE COMPOSITION BASED ON PENTAMETHYLENE 1,5-DIISOCYANATE | Covestro Deutschland AG (DE) | 2018-06-06 | — | — | EP | claimed |
| WO-2017021150-A1 | BLOCKED POLYISOCYANATE COMPOSITION BASED ON PENTAMETHYLENE 1,5-DIISOCYANATE | COVESTRO DEUTSCHLAND AG (DE) | 2017-02-09 | — | — | WO | claimed |
| US-6613934-B1 | Enzymatic partial hydrolysis of a diester of malonic acid | DEGUSSA AG (DE) | 2003-09-02 | — | — | US | claimed |
| US-12037444-B2 | Phenolic resin binder with reduced formaldehyde content | ASK CHEMICALS GMBH (DE) | 2024-07-16 | — | — | US | disclosed |
| CN-115108933-B | Synthesis method of lacosamide | 上药康丽（常州）药业有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-115108933-B | Synthesis method of lacosamide | 上药康丽（常州）药业有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-113461679-B | Synthesis of benzazepine isatin compound | 石药集团中奇制药技术（石家庄）有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-114630823-A | GLP-1R modulating compounds | 吉利德科学公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-113461679-A | Synthesis of benzazepine isatin compound | 石药集团中奇制药技术（石家庄）有限公司 | 2021-10-01 | — | — | CN | disclosed |
| WO-2017021150-A1 | BLOCKED POLYISOCYANATE COMPOSITION BASED ON PENTAMETHYLENE 1,5-DIISOCYANATE | COVESTRO DEUTSCHLAND AG (DE) | 2017-02-09 | — | — | WO | disclosed |
| US-9499469-B2 | Production method of ketomalonic acid compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20160194268-A1 | PRODUCTION METHOD OF KETOMALONIC ACID COMPOUND | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-07-07 | — | — | US | disclosed |
| US-6613934-B1 | Enzymatic partial hydrolysis of a diester of malonic acid | DEGUSSA AG (DE) | 2003-09-02 | — | — | US | disclosed |
| EP-0812819-B1 | Enantiomer-enriched tertiary hydrocarbonrest-substituted malonic acid ester and the preparation | DEGUSSA (DE) | 2001-11-28 | — | — | EP | disclosed |
| US-5831119-A | Process for the preparation of aminoacetic acids with a tertiary hydrocarbon radical in the α-position, or their nitriles | HUELS AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0812819-A2 | Enantiomer-enriched tertiary hydrocarbonrest-substituted malonic acid ester and the preparation | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194268-A1 | PRODUCTION METHOD OF KETOMALONIC ACID COMPOUND | CA6, ME1, SI | SMN1; SMN2 3342/4885CA1 105/4885CA2 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.