Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528995 | 0.94 | ALDH1A1 (0.37) | PKMCA12CA1CA7CA9 | |
| SCHEMBL7530319 | 0.91 | LMNA (0.35) | PKMKMT2AALDH1A1LMNAHTT | |
| SCHEMBL6131956 | 0.88 | SLC2A1 (0.35) | KMT2AALDH1A1LMNAHTTKDM4E | |
| SCHEMBL7528138 | 0.85 | MEN1 (0.33) | CA12CA1CA7CA9KMT2A | |
| SCHEMBL10106936 | 0.82 | SLC2A1 (0.36) | KMT2AALDH1A1LMNAHTTKDM4E | |
| SCHEMBL7525851 | 0.82 | TDP1 (0.32) | KMT2AALDH1A1LMNAHTTKDM4E | |
| SCHEMBL7534540 | 0.80 | CNR1 (0.32) | ALDH1A1LMNAHTTKDM4EMAPT | |
| SCHEMBL10102406 | 0.79 | SLC2A1 (0.36) | KMT2AALDH1A1LMNAHTTKDM4E | |
| SCHEMBL7533658 | 0.78 | PIK3CA (0.37) | KMT2AALDH1A1LMNAHTTKDM4E | |
| SCHEMBL6995620 | 0.75 | GPR84 (0.38) | KMT2AALDH1A1LMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920645-B1 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INC (US) | 2002-04-03 | — | — | EP | disclosed |
| US-6096246-A | POLYMER LENSES WITH RADIATION RESISTANT NAPHTHOPYRAN MIXTURES | CORNING INCORPORATED (US) | 2000-08-01 | — | — | US | disclosed |