Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534439 | 0.84 | NPC1 (0.32) | RAB9ANPC1KMT2ATSHRMEN1 | |
| SCHEMBL7528995 | 0.82 | ALDH1A1 (0.37) | KDM4EALDH1A1HTTHPGDGLA | |
| SCHEMBL7525851 | 0.82 | TDP1 (0.32) | MAPTKDM4EALDH1A1HTTHPGD | |
| SCHEMBL10106931 | 0.82 | MAPT (0.39) | PIK3CAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL6479818 | 0.78 | MAPT (0.38) | MAPTKDM4EALDH1A1HTTRAB9A | |
| SCHEMBL7528300 | 0.78 | PKM (0.37) | MAPTKDM4EALDH1A1HTTRAB9A | |
| SCHEMBL7528138 | 0.78 | MEN1 (0.33) | MAPTKDM4EALDH1A1HTTHPGD | |
| SCHEMBL13464678 | 0.78 | HIF1A (0.37) | PIK3CAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL7530319 | 0.77 | LMNA (0.35) | KDM4EALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL3707410 | 0.77 | HIF1A (0.34) | PIK3CAMAPTKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920645-B1 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INC (US) | 2002-04-03 | — | — | EP | disclosed |
| US-6096246-A | POLYMER LENSES WITH RADIATION RESISTANT NAPHTHOPYRAN MIXTURES | CORNING INCORPORATED (US) | 2000-08-01 | — | — | US | disclosed |
| CN-1220734-A | Naphthopyrans, compositions and articles comprising naphthopyrans | CORNING INC (US) | 1999-06-23 | — | — | CN | disclosed |