Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530247 | 0.92 | FAAH (0.44) | FAAHCES1DAGLACTSLCTSK | |
| SCHEMBL7531275 | 0.83 | TACR2 (0.49) | FAAHCES1DAGLATACR2 | |
| SCHEMBL7533012 | 0.82 | FAAH (0.45) | FAAHCES1DAGLACTSLCTSK | |
| SCHEMBL7533880 | 0.81 | TACR2 (0.52) | TACR2 | |
| SCHEMBL7535321 | 0.80 | FAAH (0.43) | FAAHCES1DAGLACTSLCTSK | |
| SCHEMBL7536597 | 0.80 | FAAH (0.43) | FAAHCES1DAGLACTSLCTSK | |
| SCHEMBL7530914 | 0.80 | FAAH (0.43) | FAAHCES1DAGLAPOLBKMT2A | |
| SCHEMBL7535950 | 0.80 | CTSL (0.49) | MAPTFAAHCES1DAGLACTSL | |
| SCHEMBL7530225 | 0.79 | CTSS (0.46) | MAPTCTSLCTSKCTSS | |
| SCHEMBL7531990 | 0.79 | ALDH1A1 (0.45) | MAPTFAAHCES1DAGLACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |