Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537367 | 0.78 | CTSK (0.42) | CTSLCTSBCTSSCTSKCES1 | |
| SCHEMBL7533228 | 0.73 | DAGLA (0.50) | CTSSCES1 | |
| SCHEMBL7530434 | 0.73 | DAGLA (0.52) | CES1 | |
| SCHEMBL7528407 | 0.69 | CTSL (0.33) | CTSLCTSBCTSSCTSKDPP4 | |
| SCHEMBL6184610 | 0.64 | CTSK (0.46) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6252796 | 0.64 | CTSK (0.46) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6252181 | 0.64 | CTSK (0.46) | CTSLCTSBCTSSCTSK | |
| SCHEMBL2678471 | 0.62 | DPP4 (0.36) | DPP4DPP8DPP7 | |
| SCHEMBL29050666 | 0.61 | ALDH1A1 (0.34) | SPHK1 | |
| SCHEMBL10447393 | 0.61 | MME (0.34) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |