Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537370 | 0.78 | POLB (0.40) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7533229 | 0.75 | FAAH (0.41) | — | |
| SCHEMBL7530436 | 0.72 | FAAH (0.43) | — | |
| SCHEMBL7528404 | 0.69 | CTSL (0.35) | CTSLCTSBCTSSCTSKDPP4 | |
| SCHEMBL6450430 | 0.66 | FAAH (0.47) | — | |
| SCHEMBL2678471 | 0.62 | DPP4 (0.36) | DPP4DPP8DPP7 | |
| SCHEMBL1153820 | 0.58 | OPRK1 (0.31) | — | |
| SCHEMBL1153199 | 0.58 | OPRK1 (0.33) | — | |
| SCHEMBL1153421 | 0.58 | OPRK1 (0.33) | — | |
| SCHEMBL1153320 | 0.58 | OPRK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |