Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530436 | 0.97 | FAAH (0.43) | FAAHCES1HSF1NPC1RAB9A | |
| SCHEMBL6450430 | 0.80 | FAAH (0.47) | FAAHCES1DAGLA | |
| SCHEMBL7533002 | 0.79 | FAAH (0.38) | FAAHCES1HSF1KMT2AXDH | |
| SCHEMBL14110504 | 0.79 | FAAH (0.51) | FAAHCES1HSF1RAB9AALDH1A1 | |
| SCHEMBL7530243 | 0.78 | LMNA (0.40) | FAAHCES1HSF1LMNAXDH | |
| SCHEMBL7535944 | 0.78 | MAPT (0.42) | FAAHCES1MAPTKMT2AXDH | |
| SCHEMBL7536589 | 0.77 | SMN1; SMN2 (0.41) | FAAHCES1HSF1NPC1RAB9A | |
| SCHEMBL7535316 | 0.77 | CTSL (0.40) | FAAHCES1ALDH1A1PPARG | |
| SCHEMBL7531988 | 0.77 | SLC6A5 (0.42) | NPC1RAB9AALDH1A1MAPTHSD17B10 | |
| SCHEMBL7530295 | 0.77 | FAAH (0.35) | FAAHCES1HSF1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |