Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528407 | 0.78 | CTSL (0.33) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7560363 | 0.74 | CTSS (0.64) | CTSLCTSBCTSSCTSKHTT | |
| SCHEMBL7533229 | 0.74 | FAAH (0.41) | NPC1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL7537367 | 0.73 | CTSK (0.42) | CTSLCTSBCTSSCTSKMCHR1 | |
| SCHEMBL7530436 | 0.71 | FAAH (0.43) | NPC1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL30968135 | 0.68 | NPC1 (0.61) | HTTNPC1RAB9AKMT2AMAPT | |
| SCHEMBL7560369 | 0.67 | CTSS (0.67) | CTSLCTSBCTSSCTSKMCHR1 | |
| SCHEMBL6450430 | 0.65 | FAAH (0.47) | — | |
| SCHEMBL30968155 | 0.65 | SMPD1 (0.61) | POLBHTTNPC1RAB9AKMT2A | |
| SCHEMBL8840247 | 0.64 | PTPN1 (0.68) | HTTNPC1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |