SCHEMBL752897

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21222589	0.86	CES2 (0.58)	TSHRMAPK1NPC1ALDH1A1POLB
	SCHEMBL27623978	0.80	ALDH1A1 (0.57)	KMT2ATSHRALDH1A1MAPTTHRB
	SCHEMBL11616860	0.75	TDP1 (0.45)	KMT2ATSHRALDH1A1POLBMAPT
	SCHEMBL2958453	0.74	LMNA (0.64)	KMT2ATSHRMAPK1NPC1ALDH1A1
	SCHEMBL11618116	0.74	PTGS2 (0.49)	TSHRNPC1ALDH1A1MAPTHPGD
	SCHEMBL238259	0.72	LTA4H (0.73)	TSHRMAPK1NPC1ALDH1A1MAPT
	SCHEMBL8572071	0.72	LTA4H (0.73)	TSHRMAPK1NPC1ALDH1A1MAPT
	SCHEMBL1736339	0.72	LTA4H (0.73)	TSHRMAPK1NPC1ALDH1A1MAPT
	SCHEMBL2892140	0.71	LMNA (0.59)	KMT2ATSHRMAPK1NPC1ALDH1A1
	SCHEMBL9421729	0.71	LMNA (0.59)	KMT2ATSHRMAPK1NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.