Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 14/20 | 0.89 |
| ▸ | MMP13 | P45452 | 14/20 | 0.89 |
| ▸ | MMP1 | P03956 | 12/20 | 0.89 |
| ▸ | ADAM17 | P78536 | 10/20 | 0.89 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | MMP2 | P08253 | 5/20 | 0.68 |
| ▸ | MMP3 | P08254 | 4/20 | 0.68 |
| ▸ | MMP8 | P22894 | 4/20 | 0.68 |
| ▸ | MMP14 | P50281 | 4/20 | 0.68 |
| ▸ | MMP7 | P09237 | 2/20 | 0.68 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.68 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406651 | 0.94 | MMP13 (1.00) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7405314 | 0.93 | SMN1; SMN2 (0.76) | MMP9MMP13MMP1ADAM17HTT | |
| SCHEMBL7510395 | 0.85 | MMP9 (0.88) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7411815 | 0.85 | MMP9 (0.69) | MMP9MMP13MMP1ADAM17HTT | |
| SCHEMBL7411525 | 0.84 | MMP9 (0.75) | MMP9MMP13MMP1ADAM17HTT | |
| SCHEMBL7407709 | 0.84 | MMP13 (1.00) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL5919409 | 0.84 | MMP13 (0.81) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7410572 | 0.83 | ALDH1A1 (0.90) | MMP9MMP13MMP1ADAM17HTT | |
| SCHEMBL5919267 | 0.83 | MMP13 (0.79) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7406031 | 0.82 | MMP13 (1.00) | MMP9MMP13MMP1ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020188120-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl, or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | AMERICAN CYANAMID COMPANY (US) | 2002-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020188120-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl, or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | MMP12, ADAM33, MMP2 | MMP9 16/4885MMP13 17/4885MMP1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.