Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533002 | 0.90 | FAAH (0.38) | CTSSCTSLFAAHCES1KMT2A | |
| SCHEMBL7535316 | 0.89 | CTSL (0.40) | CTSBCTSSCTSLTRPV1FAAH | |
| SCHEMBL7530295 | 0.89 | FAAH (0.35) | CTSBCTSSCTSLFAAHCES1 | |
| SCHEMBL7529863 | 0.88 | TACR2 (0.38) | CTSBCTSSCTSLFAAHCES1 | |
| SCHEMBL7532248 | 0.86 | CTSL (0.47) | MAPTCTSBCTSSCTSLCTSK | |
| SCHEMBL7536589 | 0.86 | SMN1; SMN2 (0.41) | MAPTCTSSFAAHCES1HDAC3 | |
| SCHEMBL7531988 | 0.85 | SLC6A5 (0.42) | MAPTHDAC3HDAC2 | |
| SCHEMBL7531423 | 0.85 | CTSL (0.39) | MAPTCTSBCTSSCTSLFAAH | |
| SCHEMBL7530243 | 0.84 | LMNA (0.40) | CTSBCTSSFAAHCES1CTSK | |
| SCHEMBL7531161 | 0.84 | CTSL (0.47) | CTSBCTSSCTSLFAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |