Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.39 |
| ▸ | CTSB | P07858 | 7/20 | 0.39 |
| ▸ | CTSS | P25774 | 7/20 | 0.39 |
| ▸ | CTSK | P43235 | 5/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532248 | 0.92 | CTSL (0.47) | CTSLCTSBCTSSCTSKCTSD | |
| SCHEMBL7531161 | 0.90 | CTSL (0.47) | CTSLCTSBCTSSCTSKCTSD | |
| SCHEMBL7535944 | 0.85 | MAPT (0.42) | CTSLCTSBCTSSCTSKFAAH | |
| SCHEMBL7533002 | 0.85 | FAAH (0.38) | CTSLCTSSCTSKFAAHCHRNA7 | |
| SCHEMBL7535316 | 0.84 | CTSL (0.40) | CTSLCTSBCTSSCTSKFAAH | |
| SCHEMBL7530295 | 0.84 | FAAH (0.35) | CTSLCTSBCTSSCTSKFAAH | |
| SCHEMBL7529863 | 0.83 | TACR2 (0.38) | CTSLCTSBCTSSCTSKTACR2 | |
| SCHEMBL7536589 | 0.81 | SMN1; SMN2 (0.41) | CTSSFAAHCES1CYP1A2POLB | |
| SCHEMBL7531988 | 0.81 | SLC6A5 (0.42) | NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7535905 | 0.80 | CTSS (0.51) | CTSLCTSBCTSSCTSKCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |