Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.47 |
| ▸ | CTSB | P07858 | 13/20 | 0.47 |
| ▸ | CTSS | P25774 | 13/20 | 0.47 |
| ▸ | CTSK | P43235 | 13/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.38 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.38 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.38 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.38 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.38 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532290 | 0.90 | CTSS (0.58) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| SCHEMBL7533810 | 0.83 | CTSL (0.54) | CTSLCTSBCTSSCTSKTACR2 | |
| SCHEMBL7530137 | 0.83 | CTSS (0.62) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7530187 | 0.81 | CTSS (0.57) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7533061 | 0.81 | CTSS (0.56) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7526705 | 0.80 | CTSS (0.55) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7530898 | 0.80 | CTSS (0.65) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7531164 | 0.80 | CTSS (0.54) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7530008 | 0.80 | CTSK (0.63) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| SCHEMBL7536001 | 0.79 | CTSL (0.55) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |