Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATF4 | P18848 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535316 | 0.82 | CTSL (0.40) | CTSLCTSBCTSSCTSKPOLB | |
| SCHEMBL7528386 | 0.80 | MAPT (0.41) | CTSLCTSBCTSSCTSKTP53 | |
| SCHEMBL7535944 | 0.79 | MAPT (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7536001 | 0.79 | CTSL (0.55) | FBP1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7533002 | 0.79 | FAAH (0.38) | KMT2ACTSLCTSSCTSKTP53 | |
| SCHEMBL7528565 | 0.78 | SMN1; SMN2 (0.40) | KMT2ACTSLCTSBCTSSCTSK | |
| SCHEMBL7530456 | 0.78 | CTSL (0.39) | FBP1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7530295 | 0.78 | FAAH (0.35) | KMT2AMEN1CTSLCTSBCTSS | |
| SCHEMBL7529863 | 0.77 | TACR2 (0.38) | CTSLCTSBCTSSCTSKTACR2 | |
| SCHEMBL7531161 | 0.77 | CTSL (0.47) | CTSLCTSBCTSSCTSKTACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |