Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530243 | 0.92 | LMNA (0.40) | HSF1ERAP1FAAHPOLBCES1 | |
| SCHEMBL7533002 | 0.83 | FAAH (0.38) | HSF1FAAHCES1CTSLCTSK | |
| SCHEMBL7535944 | 0.81 | MAPT (0.42) | MAPTFAAHCES1CTSLCTSK | |
| SCHEMBL7536589 | 0.81 | SMN1; SMN2 (0.41) | MAPTHSF1FAAHPOLBKDM4E | |
| SCHEMBL7535316 | 0.81 | CTSL (0.40) | FAAHPOLBKDM4ECES1CTSL | |
| SCHEMBL7531988 | 0.80 | SLC6A5 (0.42) | MAPTKDM4EL3MBTL1TP53TSHR | |
| SCHEMBL7530453 | 0.80 | FBP1 (0.38) | MAPTPOLBCTSLCTSKCTSB | |
| SCHEMBL7530295 | 0.80 | FAAH (0.35) | HSF1FAAHCES1CTSLCTSK | |
| SCHEMBL7529863 | 0.79 | TACR2 (0.38) | HSF1FAAHCES1CTSLCTSK | |
| SCHEMBL7530225 | 0.79 | CTSS (0.46) | MAPTAPLNRCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |