Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535944 | 0.89 | MAPT (0.42) | FAAHXDHCES1KMT2ACTSK | |
| SCHEMBL7533002 | 0.88 | FAAH (0.38) | FAAHXDHCES1HSF1TP53 | |
| SCHEMBL7535316 | 0.88 | CTSL (0.40) | FAAHCES1PTGS2CTSKALDH1A1 | |
| SCHEMBL7529863 | 0.86 | TACR2 (0.38) | FAAHCES1HSF1CTSKCTSL | |
| SCHEMBL7532248 | 0.85 | CTSL (0.47) | GAACTSKALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7536589 | 0.85 | SMN1; SMN2 (0.41) | FAAHCES1HSF1TP53USP2 | |
| SCHEMBL7531988 | 0.84 | SLC6A5 (0.42) | HTTTP53ALDH1A1LMNAALOX15 | |
| SCHEMBL7531423 | 0.84 | CTSL (0.39) | FAAHCES1CTSKALDH1A1CTSL | |
| SCHEMBL7530243 | 0.83 | LMNA (0.40) | FAAHXDHCES1HSF1CTSK | |
| SCHEMBL7531161 | 0.83 | CTSL (0.47) | FAAHHTTCES1CTSKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |