Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 9/20 | 0.36 |
| ▸ | CTSB | P07858 | 9/20 | 0.36 |
| ▸ | CTSS | P25774 | 9/20 | 0.36 |
| ▸ | CTSK | P43235 | 9/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529863 | 0.82 | TACR2 (0.38) | CTSLCTSBCTSSCTSKFAAH | |
| SCHEMBL7535316 | 0.82 | CTSL (0.40) | CTSLCTSBCTSSCTSKFAAH | |
| SCHEMBL7535944 | 0.79 | MAPT (0.42) | CTSLCTSBCTSSCTSKFAAH | |
| SCHEMBL7533002 | 0.79 | FAAH (0.38) | TP53CTSLCTSSCTSKFAAH | |
| SCHEMBL7530384 | 0.79 | CTSL (0.47) | SMN1; SMN2HPGDLMNAHTTTP53 | |
| SCHEMBL7530453 | 0.78 | FBP1 (0.38) | TP53CTSLCTSBCTSSCTSK | |
| SCHEMBL7530295 | 0.78 | FAAH (0.35) | SMN1; SMN2LMNAHTTTP53CTSL | |
| SCHEMBL7531161 | 0.77 | CTSL (0.47) | SMN1; SMN2LMNAHTTCTSLCTSB | |
| SCHEMBL7532290 | 0.77 | CTSS (0.58) | SMN1; SMN2HPGDCTSLCTSBCTSS | |
| SCHEMBL7532248 | 0.76 | CTSL (0.47) | SMN1; SMN2LMNACTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |