Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.52 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.51 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | USP8 | P40818 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530790 | 0.86 | SLC20A2 (0.65) | ACLYSLC20A2SLC20A1CCR2MEN1 | |
| SCHEMBL7537253 | 0.84 | IDH2 (0.54) | ACLYSLC20A2SLC20A1CCR2MEN1 | |
| SCHEMBL7537030 | 0.84 | MAPT (0.53) | ACLYMEN1KMT2AGPR27NPC1 | |
| SCHEMBL7532778 | 0.84 | SLC20A2 (0.54) | ACLYSLC20A2SLC20A1CCR2MEN1 | |
| SCHEMBL7533744 | 0.84 | SLC20A2 (0.58) | SLC20A2SLC20A1CCR2MEN1KMT2A | |
| SCHEMBL7533017 | 0.83 | LMNA (0.53) | ACLYMEN1KMT2AGAAAVPR2 | |
| SCHEMBL7563545 | 0.81 | CCR2 (0.48) | ACLYCCR2MEN1KMT2ANPC1 | |
| SCHEMBL7539041 | 0.81 | MEN1 (0.53) | ACLYMEN1KMT2AAVPR2GPR27 | |
| SCHEMBL7531331 | 0.80 | DHODH (0.55) | ACLYMEN1KMT2AGAA | |
| SCHEMBL28454669 | 0.80 | MEN1 (0.64) | SLC20A2SLC20A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |