Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.54 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | IDH2 | P48735 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538051 | 0.93 | HTT (0.49) | SLC20A2SLC20A1CCR2IDH2CYP1A2 | |
| SCHEMBL7537253 | 0.93 | IDH2 (0.54) | SLC20A2SLC20A1CCR2IDH2HTT | |
| SCHEMBL7530790 | 0.91 | SLC20A2 (0.65) | SLC20A2SLC20A1CCR2CYP1A2CYP3A4 | |
| SCHEMBL7531807 | 0.89 | SLC20A2 (0.53) | SLC20A2SLC20A1CCR2IDH2HTT | |
| SCHEMBL7537394 | 0.87 | SLC10A2 (0.53) | CYP1A2CYP3A4CYP2C19HTTCYP2D6 | |
| SCHEMBL7533632 | 0.87 | HTT (0.46) | SLC20A2SLC20A1IDH2CYP1A2CYP3A4 | |
| SCHEMBL7533623 | 0.87 | ACLY (0.55) | IDH2CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL7534822 | 0.85 | HTT (0.51) | IDH2CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL7533744 | 0.85 | SLC20A2 (0.58) | SLC20A2SLC20A1CCR2HTTL3MBTL1 | |
| SCHEMBL7531893 | 0.84 | HTT (0.50) | IDH2CYP1A2CYP3A4CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |