Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.52 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532778 | 0.93 | SLC20A2 (0.54) | IDH2KMT2AMEN1GAANPC1 | |
| SCHEMBL7530790 | 0.90 | SLC20A2 (0.65) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL7538051 | 0.85 | HTT (0.49) | IDH2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7533744 | 0.85 | SLC20A2 (0.58) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL7562743 | 0.84 | ACLY (0.52) | IDH2KMT2AMEN1GAANPC1 | |
| SCHEMBL7531807 | 0.83 | SLC20A2 (0.53) | IDH2KMT2AMEN1GAASLC20A2 | |
| SCHEMBL7539041 | 0.82 | MEN1 (0.53) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL1200684 | 0.82 | PARP14 (0.62) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL7538096 | 0.81 | RXFP1 (0.50) | IDH2KMT2AMEN1GAANPC1 | |
| SCHEMBL7533632 | 0.80 | HTT (0.46) | IDH2KMT2AMEN1SLC20A2SLC20A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |