Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 11/20 | 0.52 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.51 |
| ▸ | IDH2 | P48735 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534321 | 0.92 | GPR27 (0.55) | GPR27AVPR2IDH2KDM4EMAPT | |
| SCHEMBL7533441 | 0.91 | GPR27 (0.49) | GPR27KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL7530840 | 0.80 | MEN1 (0.62) | GPR27AVPR2KDM4EALDH1A1LMNA | |
| SCHEMBL7531393 | 0.79 | SLC10A2 (0.59) | GPR27AVPR2KDM4EMAPTALDH1A1 | |
| SCHEMBL7533583 | 0.75 | MEN1 (0.50) | GPR27AVPR2KDM4EMAPTALDH1A1 | |
| SCHEMBL7531883 | 0.74 | MEN1 (0.60) | GPR27AVPR2IDH2KDM4EMAPT | |
| SCHEMBL7533623 | 0.73 | ACLY (0.55) | GPR27AVPR2IDH2KDM4EMAPT | |
| SCHEMBL5126770 | 0.72 | SLC10A6 (0.67) | GPR27AVPR2KDM4EMAPTLMNA | |
| SCHEMBL7561485 | 0.72 | FADS1 (0.49) | GPR27KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL7531823 | 0.72 | MAPT (0.55) | GPR27KDM4EMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |