Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GPR27 | Q9NS67 | 8/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.47 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.47 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.47 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531393 | 0.91 | SLC10A2 (0.59) | MEN1KMT2AGPR27AVPR2KDM4E | |
| SCHEMBL7531883 | 0.89 | MEN1 (0.60) | MEN1KMT2AGPR27AVPR2KDM4E | |
| SCHEMBL14113177 | 0.85 | MEN1 (0.66) | MEN1KMT2AGPR27AVPR2KDM4E | |
| SCHEMBL7530840 | 0.82 | MEN1 (0.62) | MEN1KMT2AGPR27AVPR2KDM4E | |
| SCHEMBL7534321 | 0.81 | GPR27 (0.55) | MEN1KMT2AGPR27AVPR2KDM4E | |
| SCHEMBL14113153 | 0.80 | SLC10A6 (0.63) | MEN1KMT2AGPR27AVPR2KDM4E | |
| SCHEMBL7533361 | 0.79 | ACLY (0.48) | MEN1KMT2AGPR27AVPR2KDM4E | |
| SCHEMBL7533584 | 0.78 | METAP2 (0.56) | MEN1KMT2AKDM4EALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL7533505 | 0.76 | METAP2 (0.55) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL7533441 | 0.75 | GPR27 (0.49) | MEN1KMT2AGPR27KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |