Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533552 | 0.86 | NR1H3 (0.57) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL7537235 | 0.86 | ALDH1A1 (0.53) | SMN1; SMN2KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL7532757 | 0.85 | TSHR (0.65) | SMN1; SMN2NPC1GAAKMT2AALDH1A1 | |
| SCHEMBL7534995 | 0.84 | POLB (0.48) | SMN1; SMN2RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL7539015 | 0.79 | LMNA (0.55) | SMN1; SMN2NPC1GAARAB9AKMT2A | |
| SCHEMBL7531331 | 0.79 | DHODH (0.55) | SMN1; SMN2GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL7534382 | 0.79 | CYP2C9 (0.55) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL7568445 | 0.78 | MEN1 (0.53) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL7539025 | 0.78 | MEN1 (0.62) | SMN1; SMN2RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL7534349 | 0.78 | ACLY (0.53) | SMN1; SMN2GAARAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |