Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534349 | 0.97 | ACLY (0.53) | LMNASMN1; SMN2GPR27MEN1KMT2A | |
| SCHEMBL7533688 | 0.86 | PABPC1 (0.56) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7537204 | 0.85 | MAPT (0.51) | GPR27MEN1KMT2AACLYMAPT | |
| SCHEMBL7537030 | 0.85 | MAPT (0.53) | LMNASMN1; SMN2GPR27MEN1KMT2A | |
| SCHEMBL7533516 | 0.85 | HTT (0.50) | LMNASMN1; SMN2GPR27MEN1KMT2A | |
| SCHEMBL7531331 | 0.84 | DHODH (0.55) | LMNASMN1; SMN2MEN1KMT2AACLY | |
| SCHEMBL7569195 | 0.84 | MEN1 (0.49) | LMNAMEN1KMT2AACLYALDH1A1 | |
| SCHEMBL7568445 | 0.83 | MEN1 (0.53) | SMN1; SMN2GPR27MEN1KMT2AMAPT | |
| SCHEMBL7539025 | 0.83 | MEN1 (0.62) | LMNASMN1; SMN2GPR27MEN1KMT2A | |
| SCHEMBL7533623 | 0.83 | ACLY (0.55) | LMNASMN1; SMN2GPR27MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |