Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.44 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.44 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530740 | 0.89 | MEN1 (0.50) | MEN1KMT2AGPR27MAPTLMNA | |
| SCHEMBL7537385 | 0.88 | ACLY (0.51) | MEN1RAB9AKMT2AGPR27MAPT | |
| SCHEMBL7535071 | 0.87 | LMNA (0.47) | MEN1RAB9AKMT2AGPR27MAPT | |
| SCHEMBL7539041 | 0.85 | MEN1 (0.53) | MEN1RAB9AKMT2AGPR27TRPV4 | |
| SCHEMBL7531850 | 0.85 | ACLY (0.46) | MEN1RAB9AKMT2AMAPTLMNA | |
| SCHEMBL7531761 | 0.83 | MAPT (0.49) | MEN1KMT2AGPR27MAPTLMNA | |
| SCHEMBL7531372 | 0.82 | SLC10A2 (0.48) | MEN1RAB9AKMT2AGPR27MAPT | |
| SCHEMBL7530790 | 0.82 | SLC20A2 (0.65) | MEN1RAB9AKMT2AGPR27MAPT | |
| SCHEMBL7531845 | 0.81 | HTT (0.47) | MEN1RAB9AKMT2AGPR27MAPT | |
| SCHEMBL7534822 | 0.81 | HTT (0.51) | MEN1RAB9AKMT2AGPR27MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |