Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648603 | 0.74 | HTR3A (0.44) | HTR3A | |
| SCHEMBL5467244 | 0.70 | SLC18A3 (0.48) | — | |
| SCHEMBL7533769 | 0.69 | SLC6A2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL2803164 | 0.69 | SLC18A3 (0.47) | — | |
| SCHEMBL2277923 | 0.67 | CHRNB2 (0.53) | — | |
| SCHEMBL28533805 | 0.66 | HTR2C (0.57) | — | |
| SCHEMBL12321143 | 0.66 | HTR3A (0.61) | HTR3A | |
| SCHEMBL7014154 | 0.65 | HTR6 (0.45) | — | |
| SCHEMBL22555632 | 0.65 | USP30 (0.51) | — | |
| SCHEMBL9444151 | 0.64 | HTR3A (0.38) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100501-A4 | PYRROLIDINE AND PYRROLINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS | LILLY CO ELI (US) | 2002-12-04 | — | — | EP | disclosed |
| EP-1100501-A1 | PYRROLIDINE AND PYRROLINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000000196-A1 | PYRROLIDINE AND PYRROLINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |