Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528853 | 0.86 | POLB (0.43) | LMNAALDH1A1KMT2AHSD17B10CCR8 | |
| SCHEMBL7496325 | 0.81 | CACNA2D1 (0.41) | ALDH1A1KMT2ACACNA2D1 | |
| SCHEMBL7531036 | 0.79 | HTR6 (0.43) | HTR6LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7500612 | 0.76 | HTT (0.34) | LMNAALDH1A1KMT2ACCR8HTT | |
| SCHEMBL7493957 | 0.75 | KMT2A (0.36) | KMT2AMAPT | |
| SCHEMBL7493966 | 0.75 | KMT2A (0.36) | KMT2AMAPT | |
| SCHEMBL7499837 | 0.75 | KMT2A (0.36) | KMT2AMAPT | |
| SCHEMBL6290237 | 0.74 | HTR6 (0.40) | HTR6ALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL7497433 | 0.74 | KMT2A (0.35) | KMT2ACCR8MAPT | |
| SCHEMBL7799840 | 0.73 | POLB (0.41) | LMNAKMT2ACCR8SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022579-A2 | ANTIPSYCHOTIC SULFONAMIDE-HETEROCYCLES, AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2002-03-21 | — | — | WO | disclosed |