Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TCF4 | P15884 | 2/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537211 | 0.90 | KMT2A (0.55) | KMT2AHPGDMEN1ALDH1A1PKM | |
| SCHEMBL7533552 | 0.90 | NR1H3 (0.57) | RAB9AKMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL7530810 | 0.84 | ALDH1A1 (0.58) | KMT2ASMN1; SMN2LMNAHPGDMEN1 | |
| SCHEMBL7532088 | 0.84 | CYP2C9 (0.60) | KMT2ASMN1; SMN2LMNAHPGDMEN1 | |
| SCHEMBL7569195 | 0.84 | MEN1 (0.49) | KMT2ALMNAHPGDMEN1ALDH1A1 | |
| SCHEMBL7537945 | 0.83 | HPGD (0.67) | KMT2ASMN1; SMN2LMNAHPGDMEN1 | |
| SCHEMBL7533306 | 0.83 | KMT2A (0.54) | KMT2ASMN1; SMN2LMNAHPGDMEN1 | |
| SCHEMBL7533623 | 0.83 | ACLY (0.55) | RAB9AKMT2ASMN1; SMN2LMNAHPGD | |
| SCHEMBL7534382 | 0.82 | CYP2C9 (0.55) | RAB9AKMT2ASMN1; SMN2LMNAHPGD | |
| SCHEMBL7532549 | 0.82 | KAT6A (0.50) | RAB9AKMT2ASMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |