Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182814 | 0.88 | ITGB3 (0.54) | ENPP2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL25140726 | 0.82 | ENPP2 (0.53) | ENPP2USP30IDH1SYK | |
| SCHEMBL6182683 | 0.77 | GPR119 (0.45) | ENPP2ITGB3ITGA2BGPR119 | |
| SCHEMBL23019702 | 0.76 | LMNA (0.59) | ENPP2ALDH1A1RAB9AMAPTMAPK1 | |
| SCHEMBL18124167 | 0.76 | LMNA (0.59) | ENPP2ALDH1A1RAB9AMAPTMAPK1 | |
| SCHEMBL3900560 | 0.76 | ALDH1A1 (0.47) | ENPP2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL8318198 | 0.76 | HDAC3 (0.50) | ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL26775806 | 0.75 | USP30 (0.46) | ENPP2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL6184939 | 0.75 | ENPP2 (0.61) | ENPP2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL21876063 | 0.75 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |