Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | APEX1 | P27695 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19792777 | 0.86 | MAPT (0.44) | MAPTKMT2AMEN1APEX1RAB9A | |
| SCHEMBL20256150 | 0.80 | MAPT (0.50) | MAPTKMT2AMEN1APEX1RAB9A | |
| SCHEMBL19162426 | 0.80 | MAPT (0.50) | MAPTKMT2AMEN1APEX1RAB9A | |
| SCHEMBL7535432 | 0.78 | MAPT (0.48) | MAPTKMT2AMEN1APEX1RAB9A | |
| SCHEMBL23946310 | 0.75 | KCNH2 (0.51) | MAPTKMT2AMEN1APEX1SMN1; SMN2 | |
| SCHEMBL460367 | 0.72 | MAOA (0.56) | MAPTKMT2AMEN1APEX1RAB9A | |
| SCHEMBL23946340 | 0.72 | KCNH2 (0.46) | MAPTKMT2AMEN1APEX1SMN1; SMN2 | |
| SCHEMBL23946292 | 0.72 | KCNH2 (0.49) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL19046675 | 0.72 | KDM4E (0.49) | MAPTKMT2AMEN1APEX1RAB9A | |
| SCHEMBL19046669 | 0.72 | KDM4E (0.47) | MAPTKMT2AMEN1APEX1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10347845-B2 | Nitrogen-containing condensed cyclic compound and organic light emitting device using same | LG CHEM, LTD. (KR) | 2019-07-09 | — | — | US | disclosed |
| US-20170213984-A1 | NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | LG CHEM, LTD. (KR) | 2017-07-27 | — | — | US | disclosed |
| WO-2002030906-A1 | ANTI-TUMOUR COMPOUNDS | LA TROBE UNIVERSITY (AU) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10347845-B2 | Nitrogen-containing condensed cyclic compound and organic light emitting device using same | CRY1, NOS1, NOLC1 | MAPT 1589/4885KMT2A 1423/4885MEN1 197/4885 |
| US-20170213984-A1 | NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | CRY1, NOS1, NOLC1 | MAPT 1589/4885KMT2A 1423/4885MEN1 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.