SCHEMBL753420

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755768	0.88	LIPG (0.34)	ALDH1A1TDP1LIPGSMN1; SMN2
	SCHEMBL752339	0.85	LIPG (0.42)	ALDH1A1LIPGSMN1; SMN2POLB
	SCHEMBL754324	0.84	LMNA (0.44)	ALDH1A1HPGDCYP1A2CYP3A4USP2
	SCHEMBL751851	0.80	CYP11B1 (0.32)	ALDH1A1KDM4EHPGDTDP1LIPG
	SCHEMBL754587	0.79	JAK2 (0.41)	ALDH1A1KDM4EHPGDTDP1LIPG
	SCHEMBL12378276	0.73	MAPK1 (0.35)	ALDH1A1HPGDPARP1SMN1; SMN2POLB
	SCHEMBL754314	0.72	LIPG (0.48)	LIPGPOLB
	SCHEMBL754144	0.72	LIPG (0.42)	ALDH1A1TDP1LIPGSMN1; SMN2POLB
	SCHEMBL755059	0.72	LIPG (0.40)	ALDH1A1TDP1LIPGCYP3A4SMN1; SMN2
	SCHEMBL752862	0.72	LIPG (0.41)	ALDH1A1KDM4EHPGDTDP1LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.