Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | IDH2 | P48735 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532769 | 0.88 | MAPT (0.53) | MAPTNPC1RAB9AACLYKDM4E | |
| SCHEMBL7568445 | 0.87 | MEN1 (0.53) | MAPTGRM4GPR27KDM4EALDH1A1 | |
| SCHEMBL7533361 | 0.86 | ACLY (0.48) | MAPTACLYGRM4GPR27KDM4E | |
| SCHEMBL7534407 | 0.85 | LMNA (0.56) | MAPTNPC1RAB9AACLYGRM4 | |
| SCHEMBL7539025 | 0.85 | MEN1 (0.62) | MAPTRAB9AACLYGRM4GPR27 | |
| SCHEMBL7530740 | 0.84 | MEN1 (0.50) | MAPTACLYGRM4GPR27BDKRB1 | |
| SCHEMBL7533623 | 0.84 | ACLY (0.55) | MAPTNPC1RAB9AACLYIDH2 | |
| SCHEMBL7537030 | 0.84 | MAPT (0.53) | MAPTNPC1RAB9AACLYGRM4 | |
| SCHEMBL7537270 | 0.84 | ITGA1 (0.47) | MAPTNPC1RAB9AACLYIDH2 | |
| SCHEMBL7531372 | 0.84 | SLC10A2 (0.48) | MAPTRAB9AACLYIDH2GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |