Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534407 | 0.86 | LMNA (0.56) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL7534349 | 0.83 | ACLY (0.53) | ALDH1A1SMN1; SMN2LMNARAB9AMEN1 | |
| SCHEMBL7531709 | 0.81 | SLC40A1 (0.65) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL7531380 | 0.80 | HTT (0.52) | PABPC1ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL7531704 | 0.80 | ALDH1A1 (0.57) | NAMPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL7533710 | 0.79 | CYP3A4 (0.70) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL7537204 | 0.79 | MAPT (0.51) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7537030 | 0.79 | MAPT (0.53) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL7560629 | 0.79 | NPC1 (0.48) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL7531331 | 0.78 | DHODH (0.55) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |