SCHEMBL7535934

SCHEMBL7535934

CCOC(=S)NCc1ccccc1C=O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.38
KMT2A Q03164 4/20 0.38
MAPT P10636 3/20 0.37
POLB P06746 1/20 0.37
ALDH1A1 P00352 6/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 2/20 0.36
NPC1 O15118 2/20 0.36
HPGD P15428 3/20 0.36
MEN1 O00255 2/20 0.36
GAA P10253 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
RAB9A P51151 1/20 0.35
EPHX2 P34913 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
PPID Q08752 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535968 0.84 SMN1; SMN2 (0.45) SMN1; SMN2KMT2APOLBALDH1A1TSHR
SCHEMBL7537295 0.78 TSHR (0.48) SMN1; SMN2KMT2AMAPTALDH1A1TSHR
SCHEMBL7541780 0.77 HTT (0.51) SMN1; SMN2KMT2AMAPTPOLBALDH1A1
SCHEMBL7539730 0.76 ALDH1A1 (0.42) KMT2AMAPTALDH1A1HPGDMEN1
SCHEMBL6696629 0.76 KMT2A (0.45) KMT2AALDH1A1TSHRHTTNPC1
SCHEMBL19126687 0.73 KCNA5 (0.49) POLB
SCHEMBL15738726 0.73 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1TSHRHTTNPC1
SCHEMBL2038938 0.72 PKM (0.50) SMN1; SMN2KMT2AMAPTALDH1A1TSHR
SCHEMBL4315632 0.70 THRB (0.48) SMN1; SMN2KMT2AALDH1A1TSHRHTT
SCHEMBL27380622 0.70 LMNA (0.48) SMN1; SMN2KMT2AMAPTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 SMN1; SMN2 2971/4885KMT2A 3439/4885MAPT 3240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.