SCHEMBL7536353

SCHEMBL7536353

O=C(O)c1ccc(Oc2cc(O)c3ccccc3c2)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
GPR35 Q9HC97 1/20 0.44
CDC25B P30305 5/20 0.44
NQO2 P16083 1/20 0.44
LDHA P00338 1/20 0.43
THRB P10828 1/20 0.43
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42
NR4A3 Q92570 1/20 0.42
TTR P02766 1/20 0.42
ACMSD Q8TDX5 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MITF O75030 1/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PARP1 P09874 1/20 0.41
PARG Q86W56 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN2A Q12879 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7541806 0.82 NQO2 (0.52) NQO2
SCHEMBL14204728 0.80 CDC25B (0.53) POLBCDC25BNR4A1NR4A2NR4A3
SCHEMBL10420596 0.78 CDC25B (0.57) CDC25BLDHATHRBNR4A1NR4A2
SCHEMBL7536268 0.76 NR4A1 (0.59) POLBCDC25BLDHANR4A1NR4A2
SCHEMBL7538406 0.75 THRB (0.46) CDC25BLDHATHRBNR4A1NR4A2
SCHEMBL7539694 0.75 CDC25B (0.46) POLBGPR35CDC25BNR4A1NR4A2
SCHEMBL28802352 0.74 LMNA (0.48) POLBCDC25BMEN1KMT2AMITF
SCHEMBL7543767 0.72 CDC25B (0.52) POLBGPR35CDC25BLDHANR4A1
SCHEMBL7537740 0.72 THRB (0.54) POLBCDC25BLDHATHRBTTR
SCHEMBL7537927 0.71 ESR1 (0.43) POLBCDC25BLDHATHRBNR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 POLB 3165/4885GPR35 436/4885CDC25B 398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.