Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538406 | 0.82 | THRB (0.46) | THRBCDC25BACMSDMAPTKDM4E | |
| SCHEMBL7535711 | 0.79 | THRB (0.54) | THRBCDC25BMCL1MAPTKDM4E | |
| SCHEMBL669832 | 0.78 | THRB (0.61) | THRBCDC25BMCL1MAPTKDM4E | |
| SCHEMBL7541958 | 0.75 | MCL1 (0.41) | CDC25BMCL1MAPTKDM4EMEN1 | |
| SCHEMBL1581774 | 0.74 | IDO1 (0.65) | THRBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL7536353 | 0.72 | POLB (0.44) | THRBCDC25BACMSDKDM4EMEN1 | |
| SCHEMBL27722410 | 0.71 | MAPT (0.41) | THRBCDC25BMCL1MAPTKDM4E | |
| SCHEMBL10420596 | 0.71 | CDC25B (0.57) | THRBCDC25BMAPTKDM4EKMT2A | |
| SCHEMBL317180 | 0.71 | THRB (1.00) | THRBMCL1MAPTKDM4EMEN1 | |
| SCHEMBL11078909 | 0.71 | IDO1 (0.54) | MAPTKDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020094993-A1 | Compositions for repelling crawling insects | S.C. JOHNSON & SON, INC. | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094993-A1 | Compositions for repelling crawling insects | ACHE, DDT, GAP43 | THRB 4642/4885CDC25B 398/4885ACMSD 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.