Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711610 | 0.85 | LMNA (0.61) | RAB9AALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7536709 | 0.85 | LMNA (0.61) | RAB9AALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7533926 | 0.79 | TDP1 (0.67) | RAB9AMAPTNPC1TDP1LMNA | |
| SCHEMBL23392557 | 0.76 | LMNA (0.55) | RAB9AALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL23392559 | 0.76 | LMNA (0.55) | RAB9AALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7536698 | 0.75 | ALDH1A1 (0.41) | RAB9AALDH1A1MAPTNPC1TDP1 | |
| SCHEMBL7536762 | 0.75 | KMT2A (0.66) | RAB9AALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL5799350 | 0.73 | HDAC8 (0.78) | RAB9AALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7530445 | 0.73 | NPC1 (0.60) | RAB9AALDH1A1MAPTNPC1TDP1 | |
| SCHEMBL7195003 | 0.73 | HDAC8 (0.78) | RAB9AALDH1A1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |