SCHEMBL753735

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25542583	0.86	HDAC1 (0.47)	MAPTMAPK1HDAC1HDAC8HDAC6
	SCHEMBL753980	0.83	HDAC1 (0.51)	L3MBTL1MAPTMAPK1TDP1HDAC1
	SCHEMBL4271456	0.80	ALKBH1 (0.47)	L3MBTL1ALKBH1NUDT1PKMHTT
	SCHEMBL1163924	0.80	ALKBH1 (0.47)	L3MBTL1ALKBH1NUDT1PKMALDH1A1
	SCHEMBL1034474	0.79	NUDT1 (0.55)	L3MBTL1ALKBH1MAPTNUDT1SMN1; SMN2
	Methane SCHEMBL7252421	0.79	ALKBH1 (0.46)	L3MBTL1ALKBH1HDAC6NUDT1PKM
	SCHEMBL26985597	0.79	ALKBH1 (0.46)	L3MBTL1ALKBH1HDAC6NUDT1PKM
	SCHEMBL2524154	0.78	L3MBTL1 (0.52)	L3MBTL1MAPTMAPK1TDP1HDAC6
	SCHEMBL25465503	0.78	ALKBH1 (0.43)	L3MBTL1ALKBH1MAPTMAPK1TDP1
	SCHEMBL13729119	0.78	TRPV3 (0.44)	L3MBTL1ALKBH1MAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.